Pandemics: History

Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 "parrot fever" pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses.

How close are we to having another worldwide health crisis? Epidemiologists predict that another pandemic is coming--one that could kill hundreds of millions of people. Learn about factors that contribute to the spread of disease by examining past pandemics and epidemics. Examine case studies of potential pandemic diseases, and discover how scientists strive to contain and control the spread of disease both locally and globally. See how human activities such as global air travel and the disruption of animal habitats contribute to the risk of a new pandemic. And investigate the challenges we face with antibiotic-resistant bacteria and mutating viruses. Can scientists control the spread of disease and prevent the next pandemic?

Prizewinning science journalist Sonia Shah presents a startling examination of the history of viral infections that have ravaged humanity--and how that knowledge prepares us to stop the next worldwide outbreak. Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they've never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can't know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. InPandemic: Tracking Contagions, from Cholera to Ebola and Beyond, Shah interweaves history, original reportage, and personal narrative to explore the origins of epidemics, drawing parallels between cholera, one of history's most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.

Between the years 1918 and1920, influenza raged around the globe in the worst pandemic in recorded history, killing at least fifty million people, more than half a million of them Americans. Yet despite the devastation, this catastrophic event seems but a forgotten moment in the United States. American Pandemic offers a much-needed corrective to the silence surrounding the influenza outbreak. It sheds light on the social and cultural history of Americans during the pandemic, uncovering both the causes of the nation's public amnesia and the depth of the quiet remembering that endured. Focused on the primary players in this drama--patients and their families, friends, and community, public health experts, and health care professionals--historian Nancy K. Bristow draws on multiple perspectives to highlight the complex interplay between social identity, cultural norms, memory, and the epidemic.

The emergence of strange new diseases is a frightening problem that seems to be getting worse. In this age of speedy travel, it threatens a worldwide pandemic. We hear news reports of Ebola, SARS, AIDS, and something called Hendra killing horses and people in Australia--but those reports miss the big truth that such phenomena are part of a single pattern. The bugs that transmit these diseases share one thing: they originate in wild animals and pass to humans by a process called spillover. David Quammen tracks this subject around the world. He recounts adventures in the field--netting bats in China, trapping monkeys in Bangladesh, stalking gorillas in the Congo--with the world's leading disease scientists. In Spillover Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge, and he asks the terrifying question: What might the next big one be?

A riveting account of why science alone can't stop the next pandemic Outbreaks of avian and swine flu have reawakened fears that had lain dormant for nearly a century, ever since the influenza pandemic of 1918 that killed at least 50 million people worldwide. When a highly lethal strain of avian flu broke out in Asia in recent years and raced westward, the Washington Post's Alan Sipress chased the emerging threat as it infiltrated remote jungle villages, mountain redoubts, and teeming cities. He tracked the virus across nine countries, watching its secrets repeatedly elude the world's brightest scientists and most intrepid disease hunters. Savage and mercurial, this novel influenza strain--H5N1--has been called the kissing cousin of the Spanish flu and, with just a few genetic tweaks, could kill millions of people. None of us is immune.

The fascinating, true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse.

in the winter of 1918, at the height of WWi, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. it killed more people in twenty-four weeks than AIDS has killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research, John M. Barry's The Great influenza weaves together multiple narratives, with characters ranging from William Welch (founder of Johns Hopkins Medical School) to John D. Rockefeller and Woodrow Wilson. Ultimately a tale of triumph amid tragedy, this crisis provides a precise and sobering model for our world as we confront AIDS, bioterrorism, and other, as yet unknown, diseases.

In 1918, the Italian-Americans of New York, the Yupik of Alaska and the Persians of Mashed had almost nothing in common except for a virus--one that triggered the worst pandemic of modern times and had a decisive effect on the history of the twentieth century. The Spanish flu of 1918-1920 was one of the greatest human disasters of all time. It infected a third of the people on Earth--from the poorest immigrants of New York City to the king of Spain, Franz Kafka, Mahatma Gandhi and Woodrow Wilson. But despite a death toll of between 50 and 100 million people, it exists in our memory as an afterthought to World War I. In this gripping narrative history, Laura Spinney traces the overlooked pandemic to reveal how the virus travelled across the globe, exposing mankind's vulnerability and putting our ingenuity to the test.

A witty, irreverent tour of history's worst plagues--from the Antonine Plague, to leprosy, to polio--and a celebration of the heroes who fought them In 1518, in a small town in Alsace, Frau Troffea began dancing and didn't stop. She danced until she was carried away six days later, and soon thirty-four more villagers joined her. Then more. In a month more than 400 people had been stricken by the mysterious dancing plague. In late-seventeenth-century England an eccentric gentleman founded the No Nose Club in his gracious townhome--a social club for those who had lost their noses, and other body parts, to the plague of syphilis for whichthere was then no cure. And in turn-of-the-century New York, an Irish cook caused two lethal outbreaks of typhoid fever, a case that transformed her into the notorious Typhoid Mary. Throughout time, humans have been terrified and fascinated by the diseases history and circumstance have dropped on them. Some of their responses to those outbreaks are almost too strange to believe in hindsight.Get Well Soon delivers the gruesome, morbid details of some of the worst plagues we've suffered as a species, as well as stories of the heroic figures who selflessly fought to ease the suffering of their fellow man.

For four thousand years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since common response to the threat was exclusion--quarantining the sick or keeping them out. But the unprecedented hygiene and medical revolutions of the past two centuries have allowed humanity to free itself from the hold of epidemic cycles--resulting in an urbanized, globalized, and unimaginably wealthy world. However, our development has lately become precarious. Climate and population fluctuations and aspects of our prosperity such as global trade have left us more vulnerable than ever to newly emerging plagues. Greater global cooperation toward sustainable health is urgently required--such as the international efforts to harvest a Covid-19 vaccine--with millions of lives and trillions of dollars at stake. Written as colorful history, The Plague Cycle reveals the relationship between civilization, globalization, prosperity, and infectious disease over the past five millennia. It harnesses history, economics, and public health, and charts humanity's remarkable progress, providing a fascinating and timely look at the cyclical nature of infectious disease.

An expert legal review of the US government's response to epidemics through history--with larger conclusions about COVID-19, and reforms needed for the next plague In this narrative history of the US through major outbreaks of contagious disease, from yellow fever to the Spanish flu, from HIV/AIDS to Ebola, Polly J. Price examines how law and government affected the outcome of epidemics--and how those outbreaks in turn shaped our government. Price presents a fascinating history that has never been fully explored and draws larger conclusions about the gaps in our governmental and legal response. Plagues in the Nation examines how our country learned--and failed to learn--how to address the panic, conflict, and chaos that are the companions of contagion, what policies failed America again and again, and what we must do better next time.

NEW YORK TIMES BESTSELLER * An urgent wake-up call about the future of emerging viruses and a gripping account of the doctors and scientists fighting to protect us, told through the story of the deadly 2013-2014 Ebola epidemic.

In 1976 a deadly virus emerged from the Congo forest. As swiftly as it came, it disappeared, leaving no trace. Over the four decades since, Ebola has emerged sporadically, each time to devastating effect. It can kill up to 90 percent of its victims. In between these outbreaks, it is untraceable, hiding deep in the jungle. The search is on to find Ebola's elusive host animal. And until we find it, Ebola will continue to strike. Acclaimed science writer and explorer David Quammen first came near the virus while he was traveling in the jungles of Gabon, accompanied by local men whose village had been devastated by a recent outbreak. Here he tells the story of Ebola--its past, present, and its unknowable future.

The untold story of how America's Progressive-era war on smallpox sparked one of the great civil liberties battles of the twentieth century. At the turn of the last century, a powerful smallpox epidemic swept the United States from coast to coast. The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.

More people were killed by smallpox during the twentieth century - over 300 million - than by all of the wars of that period combined. In 1918 and 1919, influenza virus claimed over 50 million lives. A century later, influenza is poised to return, ongoing plagues of HIV/AIDS and hepatitisinfect millions, and Ebola, Zika, and West Nile viruses cause new concern and panic.The overlapping histories of humans and viruses are ancient. Earliest cities became both the cradle of civilization and breeding grounds for the first viral epidemics. This overlap is the focus of virologist/immunologist Michael Oldstone in Viruses, Plagues and History. Oldstone explains principlesof viruses and epidemics while recounting stories of viruses and their impact on human history. This fully updated second edition includes engrossing new chapters on hepatitis, Zika, and contemporary threats such as the possible return of a catastrophic influenza, and the impact of fear of autism onvaccination efforts. This is a fascinating panorama of humankind's longstanding conflict with unseen viral enemies, both human successes - such as control of poliomyelitis, measles, smallpox and yellow fever, and continued dangers - such as HIV and Ebola. Impeccably researched and accessiblywritten, Viruses, Plagues and History will fascinate all with an interest in how viral illnesses alter the course of human history.

In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it? Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand--Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa's chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not - and the region's health care woes worsened, with devastating consequences that Farmer traces up to the present. T

From the masters of storytelling-meets-science and co-authors of Quackery, Patient Zero tells the long and fascinating history of disease outbreaks - how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us.

A world-leading epidemiologist shares his stories from the front lines of our war on infectious diseases and explains how to prepare for epidemics that can challenge world order. Unlike natural disasters, whose destruction is concentrated in a limited area over a period of days, and illnesses, which have devastating effects but are limited to individuals and their families, infectious disease has the terrifying power to disrupt everyday life on a global scale, overwhelming public and private resources and bringing trade and transportation to a grinding halt. In today's world, it's easier than ever to move people, animals, and materials around the planet, but the same advances that make modern infrastructure so efficient have made epidemics and even pandemics nearly inevitable. And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy? Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons,

An inside account of the fight to contain the world's deadliest diseases--and the panic and corruption that make them worse Throughout history, humankind's biggest killers have been infectious diseases: the Black Death, the Spanish Flu, and AIDS alone account for over one hundred million deaths. We ignore this reality most of the time, but when a new threat--Ebola, SARS, Zika--seems imminent, we send our best and bravest doctors to contain it.

Do cell phones cause brain cancer? Does BPA threaten our health? How safe are certain dietary supplements, especially those containing exotic herbs or small amounts of toxic substances? Is the HPV vaccine safe? We depend on science and medicine as never before, yet there is widespread misinformation and confusion, amplified by the media, regarding what influences our health. In Getting Risk Right, Geoffrey C. Kabat shows how science works--and sometimes doesn't--and what separates these two very different outcomes. Kabat seeks to help us distinguish between claims that are supported by solid science and those that are the result of poorly designed or misinterpreted studies. By exploring different examples, he explains why certain risks are worth worrying about, while others are not. He emphasizes the variable quality of research in contested areas of health risks, as well as the professional, political, and methodological factors that can distort the research process. Drawing on recent systematic critiques of biomedical research and on insights from behavioral psychology, Getting Risk Right examines factors both internal and external to the science that can influence what results get attention and how questionable results can be used to support a particular narrative concerning an alleged public health threat.

On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure? While influenza is now often thought of as a common and mild disease, it still kills over 30,000 people in the US each year. Dr. Jeremy Brown, currently Director of Emergency Care Research at the National Institutes of Health, expounds on the flu's deadly past to solve the mysteries that could protect us from the next outbreak. In Influenza, he talks with leading epidemiologists, policy makers, and the researcher who first sequenced the genetic building blocks of the original 1918 virus to offer both a comprehensive history and a roadmap for understanding what's to come. Dr. Brown digs into the discovery and resurrection of the flu virus in the frozen victims of the 1918 epidemic, as well as the bizarre remedies that once treated the disease, such as whiskey and blood-letting. Influenza also breaks down the current dialogue surrounding the disease, explaining the controversy over vaccinations, antiviral drugs like Tamiflu, and the federal government's role in preparing for pandemic outbreaks. Though 100 years of advancement in medical research and technology have passed since the 1918 disaster, Dr. Brown warns that many of the most vital questions about the flu virus continue to confound even the leading experts. Influenza is an enlightening and unnerving look at a shapeshifting deadly virus that has been around long before people--and warns us that it may be many more years before we are able to conquer it for good.

Quarantine is our most powerful response to uncertainty: it means waiting to see if something hidden inside us will be revealed. It is also one of our most dangerous, operating through an assumption of guilt. In quarantine, we are considered infectious until proven safe. Until Proven Safe tracks the history and future of quarantine around the globe, chasing the story of emergency isolation through time and space--from the crumbling lazarettos of the Mediterranean, built to contain the Black Death, to an experimental Ebola unit in London, and from the hallways of the CDC to closed-door simulations where pharmaceutical execs and epidemiologists prepare for the outbreak of a novel coronavirus. But the story of quarantine ranges far beyond the history of medical isolation. In Until Proven Safe, the authors tour a nuclear-waste isolation facility beneath the New Mexican desert, see plants stricken with a disease that threatens the world's wheat supply, and meet NASA's Planetary Protection Officer, tasked with saving Earth from extraterrestrial infections. They also introduce us to the corporate tech giants hoping to revolutionize quarantine through surveillance and algorithmic prediction.